A Complete Review on Solid Dispersion Technology and Factorial Design.
نویسندگان
چکیده
منابع مشابه
Solid Dispersion- an Approach to Enhance the Dissolution Rate of Aceclofenac by Using 3 Factorial Design
Aceclofenac is an analgesic and anti-inflammatory agent used in the management of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. The objective of the present work was to investigate the effect of different types of carriers such as polyvinyl pyrrolidone (PVP), polyethylene glycol (PEG) 6000 and sodium lauryl sulphate (SLS) as solubilizer on in vitro dissolution of aceclofenac....
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In recent years due to the demonstration of destructive side effects of chemical drugs, utilizing herbal drugs to treat diseases have increased. The medicinal Vaccinium is one of the popular plants which have many pharmaceutical, food and industrial values. There are about 100 species of this genus around the world but Ghare-Ghat (Vaccinium arctostaphlyus) is the only species present in Iran wh...
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Solid lipid nanoparticles of atovaquone (ATQ-SLN) were prepared by high shearhomogenization method using tripalmitin, trilaurin, and Compritol 888 ATO as the lipidmatrices and Phospholipon 90H, Tween 80, and poloxamer 188 as the surfactants. Optimizationof the formulations was conducted using 6 sets of 24 full-factorial design based on fourindependent variables that were the number of homogeniz...
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Solid lipid nanoparticles of atovaquone (ATQ-SLN) were prepared by high shearhomogenization method using tripalmitin, trilaurin, and Compritol 888 ATO as the lipidmatrices and Phospholipon 90H, Tween 80, and poloxamer 188 as the surfactants. Optimizationof the formulations was conducted using 6 sets of 24 full-factorial design based on fourindependent variables that were the number of homogeniz...
متن کاملFormulation and Characterization of Solid Dispersions of Glimepiride through Factorial Design
In order to enhance in vitro dissolution and content uniformity of poorly soluble drug glimepiride by preparing solid dispersions using modified solvent fusion method, solid dispersions of drug were prepared by modified fusion solvent method using PEG 6000 and PVP K25 (as carrier). Eight batches (F1-F8) were prepared by Factorial design (23) by taking three ...
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ژورنال
عنوان ژورنال: Journal of Current Pharma Research
سال: 2012
ISSN: 2230-7834,2230-7842
DOI: 10.33786/jcpr.2012.v02i04.011